Aliaxin GP 1x1ml

Injectable filler: for medical professionals only. Aliaxin GP is injected into the mid and deep dermis; the final technique and dose are chosen by the specialist. Do not inject into blood vessels. This pack variant contains 1 pre-filled 1 ml syringe and 27G × 13 mm and 27G × 19 mm needles.

What is Aliaxin GP 1 ml?

Aliaxin GP Global Performance is a resorbable medical device in the form of a sterile cross-linked hyaluronic acid gel, intended for the correction of medium and deep facial skin sagging and for increasing lip volume and contour. It belongs to the Aliaxin filler line by IBSA Farmaceutici Italia. Its stiffness (G′ 95 Pa) is intermediate between the soft Aliaxin FL and the volumising Aliaxin EV, which makes it suitable for correcting folds and wrinkles and for moderate volumisation. See also other dermal fillers.

Composition

• Cross-linked hyaluronic acid: 25 mg/ml, combining two molecular weights: 1000 kDa and 2000 kDa.
• Phosphate buffer and water for injection: gel carrier up to 1 g.

The product does not contain lidocaine. Local anaesthesia may be applied separately if the physician considers it appropriate. The hyaluronic acid is of non-animal origin, produced by biofermentation.

Mechanism of action

The gel is injected into the skin tissue to supplement the extracellular matrix and increase intradermal volume. It smooths skin depressions caused by wrinkles and scars and locally restores soft-tissue volume. The combination of high-molecular-weight hyaluronic acid gives a gel with a corrective and lifting action while preserving natural facial expression. The effect is temporary: the hyaluronic acid is gradually resorbed.

Indications and treatment areas

Aliaxin GP is intended for restoring physiological facial volumes and correcting imperfections in the following areas:

• nasolabial folds,
• marionette lines,
• perioral wrinkles,
• glabellar lines and forehead wrinkles,
• facial scars and acne scars,
• areas requiring tissue enrichment with a temporary increase in volume: cheeks, chin, cheekbones, lips.

Results depend on skin type, anatomy and the nature of the imperfection. More products for deep wrinkles.

Administration: injection plane and parameters

• Injection plane: mid and deep dermis. The final technique and depth are at the physician's discretion and depend on the planned correction.
• Rheological parameters: G′ 95 Pa, tan δ 0.23: a gel of medium stiffness, combining wrinkle correction with a moderate volumising effect.
• HA molecular weights: 1000 kDa and 2000 kDa.
• Needles included: 27G × 13 mm and 27G × 19 mm needles.
• Dosage: the volume per area is at the specialist's discretion.
• The procedure is performed under aseptic conditions, observing the standard precautions for percutaneous procedures.

Duration of effect

The duration of the effect is individual and usually 6-12 months, depending on the injection technique, treated area, metabolism and the patient's predisposition.

Contraindications and precautions

Do not use in case of hypersensitivity to hyaluronic acid, during pregnancy and breastfeeding, with active skin infections or inflammation at the injection site, in autoimmune diseases or in patients prone to keloids. Do not inject into blood vessels.

Packaging and product data

• Pack (this shop variant): 1 sterile pre-filled 1 ml syringe (single use) + 1 needle 27G × 13 mm + 1 needle 27G × 19 mm.
• EAN: 8033638950500.
• Manufacturer: IBSA Farmaceutici Italia S.r.l., Via Martiri di Cefalonia 2, 26900 Lodi, Italy.

Frequently asked questions

How does Aliaxin GP differ from the other products in the Aliaxin line?

The whole Aliaxin line has the same concentration of cross-linked hyaluronic acid, 25 mg/ml, and the differences come from rheological properties and intended use. GP (Global Performance) is a medium-stiffness gel (G′ 95 Pa, tan δ 0.23) for folds, wrinkles and moderate volumisation, injected into the mid and deep dermis. Aliaxin FL (Fine Lines & Lips) is a soft gel (G′ 45 Pa, tan δ 0.39) for lip contour, lip hydration and fine lines. Aliaxin EV (Essential Volume) is a firmer gel (G′ 162 Pa, tan δ 0.15) for volume restoration and contouring, injected subcutaneously. LV (Lips Volume) is for lip volume; SR (Shape & Restore) for shaping and restoring the facial oval; SV (Superior Volume) for greater volumisation. Product selection is up to the specialist.

Aliaxin GP or Aliaxin EV: which one to choose?

GP is chosen mainly for correcting more pronounced wrinkles and folds (e.g. nasolabial folds, marionette lines) and for moderate volume restoration in the dermis. EV is intended for restoring greater volume loss and contouring the face in the subcutaneous tissue. The final choice depends on the physician's assessment.

What is the difference between the 1×1 ml and 2×1 ml packs?

This product is a single pre-filled 1 ml syringe with two needles (27G × 13 mm and 27G × 19 mm). The Aliaxin GP 2×1 ml variant is the manufacturer's standard pack: two syringes and four needles. The gel is the same.

At what depth is Aliaxin GP injected?

The product is injected into the mid and deep dermis. The final technique and depth are at the physician's discretion and depend on the planned correction.

How long does the effect last?

The duration of the effect is individual and usually 6-12 months, depending on the injection technique, treated area, metabolism and the patient's predisposition.

Does Aliaxin GP contain lidocaine?

No. It contains cross-linked hyaluronic acid 25 mg/ml, phosphate buffer and water for injection. Local anaesthesia can be applied separately if the physician considers it appropriate.

Who may use this product?

Medical professionals only, in accordance with the current instructions for use and applicable regulations. By purchasing the product you declare that you are authorised to perform procedures that break the continuity of tissues.

Information for specialists

For use by medical professionals only. Before treatment, take a medical history and assess the patient for contraindications, inform the patient about the nature of the procedure, possible risks and post-treatment recommendations, and follow the current instructions for use.

Do not inject intravascularly. Particular caution and knowledge of anatomy are required in areas of higher vascular risk, including the glabella and the nasolabial region. The syringe and needles are sterile and single-use; discard any remaining product and do not use if the packaging is damaged. Included: 27G × 13 mm and 27G × 19 mm needles.

As with any injection, transient reactions may occur: mild swelling, redness, tenderness or small bruises, which usually resolve spontaneously within a few days.

Table of contents

• What is Aliaxin GP 1 ml?
• Composition and mechanism of action
• Indications, administration and product data
• Frequently asked questions
• Information for specialists